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Antidepressants + Stress + High-Fat Diet = Long-Term Weight Gain

June 19, 2013: 12:00 AM EST
Taking antidepressants even for a short period of time can lead to significant weight gain when combined with stress and a high-fat diet, according to an Australian study in rats. The finding is significant because millions of prescriptions for antidepressants are written each year -- at the same time that obesity rates are climbing. For the study, male rats were treated with the antidepressant fluoxitine after induced stress. These animals had significantly higher weight gain than control animals. Researchers concluded that short-term exposure to stress and antidepressants – rather than a high-calorie, high-fat diet alone – leads to long-term body weight gain.
Suhyun Lee et al., "Relationship Between Short-Term Antidepressant Use, Stress, High-Fat Diet And Long-Term Weight Gain", News release, study presented at the Endocrine Society annual meeting, June 19, 2013, via Medical News Today, © MediLexicon International Ltd
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