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Human Intestinal Bacteria Shown To Remove E. Coli Toxins In Mouse Study

May 20, 2013: 12:00 AM EST
U.S. researchers have shown in mice that normal human intestinal bacteria can prevent the accumulation of toxins caused by the presence of the dangerous foodborne pathogen E. coli. The bacteria has been responsible for several recent outbreaks of disease that led to hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS), a form of acute renal disease that can result in death or permanent disability. For the study, mice pre-colonized with a mixture of non-pathenogenic bacteria that occur naturally in the human gut remained completely healthy after E. Coli toxins were introduced. The control group, however, had high levels of toxins and all developed kidney disease within a week of infection.
Kathryn Eaton et al., "Intestinal Bacteria Protect Against E Coli O157:H7", News release, presentation at the general meeting of the American Society for Microbiology, May 20, 2013, © American Society for Microbiology
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