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Researchers Find That Sucralose Affects Glucose And Insulin Response

May 29, 2013: 12:00 AM EST
U.S. researchers have found evidence that sucralose, the main ingredient of the sweetener  Splenda, does not pass through the body without effect. Obese participants without diabetes drank water followed by glucose, then sucralose followed by glucose. When they drank sucralose, their blood sugar peaked at a higher level than when they drank only water before consuming glucose. Sucralose therefore affects the glucose and insulin response to glucose ingestion, though the researchers acknowledged they do not yet understand the mechanism responsible for the response. Further studies are needed to determine the long-term metabolic impact of sucralose consumption.
M. Y. Pepino et al., "Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load", Diabetes Care, May 29, 2013, © American Diabetes Association
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